Toru Sakai
Goh Omura / Doctor Obler / Obular Brain (voice)

Seiro Yamaguchi
Tetsuya Yano / Black Bison / Robo Brain (voice)

Yutaka Hirose
Kenji Tsukigata / Doctor Kemp / Terror Beast Brain (voice)

嶋大輔
Yusuke Amamiya / Red Falcon

西村和彦
Jo Oohara / Yellow Lion

Megumi Mori
Megumi Misaki / Blue Dolphin

Jin Kawamoto
Jun'ichi Aikawa / Green Sai

高坂真琴
Colon (voice)

中田譲治
Great Professor Bias

Akiko Amamatsuri
Rui Senda / Doctor Mazenda

桑原たけし
Narrator

丸山詠二
Engine Brain (voice) / Vega Brain (voice) / Test Brain (voice) / Guitar Brain (v...

岸野一彦
Anger Brain (voice) / Invisible Brain (voice) / Sword Brain (voice) / Hacker Bra...

徳丸完
Transmission Brain (voice) / Shark Brain (voice) / Maze Brain (voice)

宗方奈美
Toshiko Omura

Toshihiko Nakano
Gou Omura (child)

依田英助
Fire Brain (voice) / Regeneration Brain (voice) / Spirit Brain (voice)

伴大介
Doctor Hoshi

高杉哲平
Shosaburo

Ryohei Iizuka
Kenichi