Eric McCormack
Lucky (voice)

René Auberjonois
McLeish (voice)

Yvette Nicole Brown
Cookie (voice)

John DiMaggio
Niblet (voice)

Alanna Ubach
Strudel / Mr. Nut Nut (voice)

Michael Rapaport
Squirt (voice)

M. Emmet Walsh
Olaf (voice)

Brooke Goldner
Rebound (voice)

E. G. Daily
Dolly (voice) / Ian (voice) / Twiggy / Dolly (voice) / Daphne / Mom (voice) / Mi...

Cree Summer
Cupcake (voice) / Cupcake / Katy's Mom (voice) / Cupcake / Runt (voice) / Cupcak...

Jeff Bennett
Claudio / Crew Man #1 / Yorkie #2 (voice) / Dad / Agent Gus / Sir Winston Windmi...

Jessica DiCicco
Patches (voice) / Tommy / Allyson / Sweetie (voice) / Sweet Pea / Vladibulbanian...

Kath Soucie
Jennifer / Millard's Mom / Dot's Mom (voice) / Ginger / Mom / Girl (voice) / Mol...

Betty White
Agatha McLeish (voice)

Tress MacNeille
Tommy's Mom / Alley Dog #1 / FKD (voice) / Pickypuss / Matron / Groomer #1 (voic...

Grey DeLisle
Teen Boy's Mom / Tabitha (voice) / Katy / Pet Owner (voice) / Puddles / Lillian ...

Tara Strong
Dolores / Old Person (voice) / Madeline / Eve / Mom Gardener (voice) / Carlyle /...

Pamela Adlon
Gwen (voice) / Taboo (voice) / Seymor (voice) / Benji / Officer Meyer (voice) / ...

Kevin Michael Richardson
Ringbinder / Bumbles / Announcer (voice) / Sid / Chubba / Sven (voice) / Saint B...

Danny Cooksey
Chip / Biker (voice) / Chucky (voice) / Humphrey (voice) / Chubby Puppy / Securi...