Eric Wareheim
Various

Tim Heidecker
Various

John C. Reilly
Dr. Steve Brule / Dr. Steve Brule (uncredited)

Bob Odenkirk
Cinco Announcer (voice) / Announcer (voice) / Various / Danny Mothers (uncredite...

Richard Dunn
Self / / Pep Pep / Old Office Temp / Tim's Body / Tim's Dad

David Liebe Hart
Self

James Quall
Self

Bill A. Jones
Announcer (voice) / Channel 5 Announcer (voice) / Infomercial Announcer (voice) ...

Ben Hur
Self /

Ron Austar
Pierre / Pierre (uncredited) / Bride's Parents

Bob Druwing
Self / Chanter / Lindsay Porch / Child Clown Video Instructor (voice)

'Weird Al' Yankovic
Uncle Muscles / Simon

Warren Stearns
Self / Old Office Temp / Pastor / Self / Audience Member (uncredited) / Gravy Ro...

Kazu Nagahama
Kaz / Kaz / E-Jury Guy / Tiny Hat Wearer / Self / Birthday Party Guest / Mourner

Zach Galifianakis
Tairy Greene / Tairy Greene as The Snuggler

Will Forte
Pall Willeaux / Will Grello / J.J. Pepper / Dr. Reid Tamaranda

Joey Brander
Seminar Student / Joey Heidecker

Rainn Wilson
Blind Man / Cinco Spokesman / Bobby Stoan / Bobby Stoan (uncredited) / Video Mat...

Palmer Scott
Self / Sit on You Guy / Sit On You Guy

Tanese Gray
Self / Game Player