David Kaufman
Stuart Little (voice)

Myles Jeffrey
George Little (voice)

Jennifer Hale
Eleanor Little / Martha Little (voice)

Hugh Laurie
Mr. Frederick Little (voice)

André Sogliuzzo
Monty (voice)

Kevin Schon
Snowbell (voice)

Quinton Flynn
(voice) / Snowbell (voice)

Dee Bradley Baker
(voice) / Additional Voices (voice)

Marc John Jefferies
Will (voice)

Edie McClurg
(voice)

Mark Hamill
(voice) / Falcon (voice)

Jeffrey Jones
Uncle Crenshaw Little (voice)

Julie Nathanson
(voice)

Kathy Najimy
Margalo (voice)

Rachael Harris
(voice)

Robert Costanzo
(voice)

Debi Derryberry
(voice)

Jim Wise
(voice)

Ken Hudson Campbell
(voice)

Daniel Hansen
(voice)