Cary Grant
C.K. Dexter Haven

Katharine Hepburn
Tracy Lord

James Stewart
Macaulay 'Mike' Connor

Ruth Hussey
Elizabeth 'Liz' Imbrie

John Howard
George Kittredge

Roland Young
Uncle Willie

John Halliday
Seth Lord

Mary Nash
Margaret Lord

Virginia Weidler
Dinah Lord

Henry Daniell
Sidney Kidd

Lionel Pape
Edward

Rex Evans
Thomas

King Baggot
Wedding Guest (uncredited)

Hillary Brooke
Main Line Society Woman (uncredited)

Veda Buckland
Elsie (uncredited)

Lita Chevret
Manicurist (uncredited)

Russ Clark
John the Chauffeur (uncredited)

David Clyde
Mac (uncredited)

Robert De Bruce
Dr. Parsons (uncredited)

Dorothy Fay
Main Line Society Woman (uncredited)