Alyson Stoner
Little Engine (voice)

Whoopi Goldberg
The Tower (voice)

Patrick Warburton
The Caboose (voice)

Jeff Bennett
Hudson

Hudson

Jodi Benson
Jillian (voice)

Corbin Bleu
Lou (voice)

Jim Cummings
Rusty (voice)

Jamie Lee Curtis
Beverly (voice)

Chelsea Evered
Girl Train (voice)

Khamani Griffin
Marcus (voice)

Dominic Scott Kay
Richard (voice)

Mocean Melvin
Big Locomotive (voice)

Suzy Nakamura
Teacher (voice)

Ray Porter
Nightmare Train (voice)

Michael S. Garcia
Scott (voice as Michael Rodrigo)

Rodney Saulsberry
Freight Train

Freight Train

Charlie Schlatter
Major (voice)

Brenda Song
Shiny Passenger Train (voice)