T-Pain
Freaknik (voice)

Joey Galaxy
Virgil (voice)

Cee Lo Green
Lite Skinn'd (voice)

Rick Ross
Big Uzi (voice)

Lil' Jon
Foreboding Old Dude (voice)

Big Boi
Preacher (voice)

DJ Drama
Mr. Thanksgiving (voice)

Snoop Dogg
Gang Member (voice)

Kelis
(voice)

Mack Maine
(voice)

Sophia Fresh
Leacosia / Toprameneesha / Obamaniqua / Suzie (voice)

Lil Wayne
Trap Jesus (voice)

Charlie Murphy
(voice)

Bill Hader
Tad (voice)

Andy Samberg
Chad (voice)

George Clinton
(voice)

Bootsy Collins
(voice)

Kel Mitchell
Fruit Bowl Boys Leader (voice)

Liz Benoit
Oprah Winfrey (voice)

Gene Anderson
(voice)