Cary Grant
Mortimer Brewster

Priscilla Lane
Elaine Harper Brewster

Josephine Hull
Aunt Abby Brewster

Jean Adair
Aunt Martha Brewster

Raymond Massey
Jonathan Brewster

John Alexander
'Teddy Roosevelt' Brewster

Peter Lorre
Dr. Einstein

Jack Carson
Officer Patrick O'Hara

Edward Everett Horton
Mr. Witherspoon

James Gleason
Lt. Rooney

Grant Mitchell
Reverend Harper

Edward McNamara
Sergeant Brophy

Garry Owen
Taxi Cab Driver

John Ridgely
Officer Saunders

Vaughan Glaser
Judge Cullman

Chester Clute
Dr. Gilchrist

Charles Lane
Reporter at Marriage License Office

Edward McWade
Gibbs

Hank Mann
Photographer at Marriage License Office (uncredited)

Spencer Charters
Marriage License Clerk