Tyler Posey
Inferno (voice) / Dante Pertuz (voice)

Milana Vayntrub
Doreen Green / Squirrel Girl (voice)

Dove Cameron
Gwen Stacy / Ghost-Spider (voice)

Chloe Bennet
Daisy Johnson / Quake (voice)

Kathreen Khavari
Kamala Khan / Ms. Marvel (voice)

Steven Weber
Capt. George Stacy (voice)

Skai Jackson
Gloria Grant (voice)

Dee Bradley Baker
Tippy Toe (voice)

Kamil McFadden
Rayshaun Lucas / Patriot (voice)

Max Mittelman
Kevin (voice)

Tara Strong
Mary Jane Watson (voice)