K.J. Apa
Archie Andrews

Lili Reinhart
Betty Cooper

Camila Mendes
Veronica Lodge

Cole Sprouse
Jughead Jones

Madelaine Petsch
Cheryl Blossom

Casey Cott
Kevin Keller

Mädchen Amick
Alice Cooper

Vanessa Morgan
Toni Topaz

Charles Melton
Reggie Mantle

Drew Ray Tanner
Fangs Fogarty

Mark Consuelos
Hiram Lodge

Martin Cummins
Tom Keller / Tom Keller / Mayor Keller

Marisol Nichols
Hermione Lodge / Hermione Lodge / Apollonia Gomez / Hermione Lodge (voice)

Skeet Ulrich
FP Jones

Alvin Sanders
Pop Tate

Nathalie Boltt
Penelope Blossom

Barbara Wallace
Nana Rose Blossom

Lochlyn Munro
Hal Cooper

Luke Perry
Fred Andrews

Erinn Westbrook
Tabitha Tate