Bill Burr
Frank Murphy (voice)

Laura Dern
Sue Murphy (voice)

Justin Long
Kevin Murphy (voice)

Haley Reinhart
Bill Murphy (voice)

Debi Derryberry
Maureen Murphy / Bridget Fitzsimmons / Phillip Bonfiglio (voice)

Sam Rockwell
Vic (voice)

David Koechner
Bob Pogo (voice)

Kevin Michael Richardson
Rosie Roosevelt (voice) / Rosie (voice)

Trevor Devall
Otto Holtenwasser / Goomer / Bolo (voice)

Mo Collins
Vivian Saunders / Lex / Ginny Throater / Nana Rose (voice)

Kevin Farley
Babe Bonfiglio (voice)

Phil Hendrie
Jim Jeffords (voice)

Vince Vaughn
Chet Stevenson (voice)

Gary Cole
Roger Dunbarton (voice)

T.J. Miller
Randy (voice)

Brooke Dillman
Lifted Riffs Lead Singer (voice)

Joe Buck
Louis Gagliardi (voice)