Adewale Akinnuoye-Agbaje
Major Lazer (voice)

James Adomian
General Rubbish (voice)

John Boyega
Blkmrkt (voice)

Ashante 'Taranchyla' Reid
Old Rasta / PG Tipps / Weed Man (voice)

J.K. Simmons
President Whitewall (voice)

Angela Trimbur
Penny Whitewall (voice)

Jorma Taccone
K-POP (voice) / Killscreen (voice) / Spooky Dookie (voice)

Andy Samberg
Dr. Nerd (voice) / DJ Nerd (voice)

Riff Raff
Double Cup (voice) /

Trinidad James
Weed Man (voice) / Goldie (voice)

Matt Berry
Professor Teacher (voice)

Jonathan Banks
The Law (voice)

Tiësto
DJ God (voice)

Udo Kier
Head Vampire Vampire (voice)

Ezra Koenig
Ryland (voice)

Aziz Ansari
Goosh (voice)

Kumail Nanjiani
Thor (voice)

Clyde Kusatsu
Store Owner (voice)

Cat Power
Knife Fight (voice)

Mike Skinner
Blockhead (voice)