Tara Strong
Ben Tennyson (voice)

Meagan Moore
Gwen Tennyson (voice)

Paul Eiding
Grandpa Max (voice)

Dee Bradley Baker
Stinkfly / Wildmutt (voice) / Wildmutt / Bullie #1 / Robotic Lt. (voice)

Steve Blum
Ghostfreak / Heatblast / Vilgax (voice)

Richard McGonagle
Four Arms (voice)

Jim Ward
Diamondhead / Wildvine / XLR8 (voice) / Diamondhead / XLR8 (voice)

Fred Tatasciore
Cannonbolt (voice) / Cannonbolt / Ripjaws (voice) / Ripjaws (voice) / Ripjaws / ...

Richard Steven Horvitz
Grey Matter (voice)

Khary Payton
Hex (voice) / Foreman / Forever Knight #1 (voice) / Automated Voice (voice) / Co...

Richard Doyle
Enoch (voice) / Dr. Shueman (voice) / Mr. Jingles (voice)

Dwight Schultz
Dr. Animo (voice) / Earl (voice)

Charlie Schlatter
Kevin Levin (voice)

Jennifer Hale
Teacher / Jamie (voice) / Gilbert / Mandy (voice) / Joey (Rojo) (voice)

Kari Wahlgren
Charmcaster (voice) / Grey Matter Gwen (voice)

Vanessa Marshall
Tini (voice) / Diamond Head Gwen / Four Arms Gwen (voice) / Female Cannonbolt / ...

Tom Kane
Ultimos (voice) / Donovan (voice)

Kim Mai Guest
Pinky / Kid (voice) / Elsgood / Grandkid / Kid #1 (voice) / Andy (voice)

Kath Soucie
Little Boy / Tiffany (voice) / Joan / Teen #2 / Cowgirl (voice) / Edwin (voice)

Cree Summer
Frightwig (voice)