Scott Aukerman
Self - Host

Reggie Watts
Self - Co-Host / Self

Kid Cudi
Self - Co-Host / Self

'Weird Al' Yankovic
Self - Co-Host / Self / Mike Cankers

Paul F. Tompkins
Sir Andrew Lloyd Webber / Lord Andrew Lloyd Webber / Werner Herzog / J.W. Stillw...

Zach Galifianakis
Self

Paul Rust
Jack Blade / Various / Self

Mary Holland
Bathroom Patron / Magpie / Julie / Creepy Couple

Andy Daly
Don Dimello / Chip Gardner / Danny Mahoney

Jason Mantzoukas
Chef Luigi Lugosi / Self

Gillian Jacobs
Self / Post-Apocalypse Woman

Andy Samberg
Self

Brett Gelman
Dog Lawyer / Mr. Celebrity / Self

Nick Kroll
Fabrice Fabrice / El Chupacabra

Jerry Minor
Mailman Manny / Fred Dumphrey

Matt Besser
Richard Uptill / Hooch the Mooch / Sheriff

James Adomian
Jesse Ventura / Giles Duggard

Grant Palmer
Leland

Michael Cera
Self

Tim Heidecker
Phil Gorsley