Scott Aukerman
Self - Host

Reggie Watts
Self - Co-Host / Self

Kid Cudi
Self - Co-Host / Self

'Weird Al' Yankovic
Self - Co-Host / Self / Mike Cankers

Paul F. Tompkins
Lord Andrew Lloyd Webber / Sir Andrew Lloyd Webber / Werner Herzog / Alan Thicke...

Zach Galifianakis
Self

Paul Rust
Jack Blade / Self / Various

Mary Holland
Bathroom Patron / Creepy Couple / Julie / Magpie

Andy Daly
Don Dimello / Danny Mahoney / Chip Gardner

Jason Mantzoukas
Chef Luigi Lugosi / Self

Gillian Jacobs
Self / Post-Apocalypse Woman

Andy Samberg
Self

Brett Gelman
Dog Lawyer / Mr. Celebrity / Self

Nick Kroll
Fabrice Fabrice / El Chupacabra

Jerry Minor
Mailman Manny / Fred Dumphrey

Matt Besser
Richard Uptill / Sheriff / Hooch the Mooch

James Adomian
Jesse Ventura / Giles Duggard

Grant Palmer
Leland

Michael Cera
Self

Tim Heidecker
Phil Gorsley