Grey DeLisle
Emily Elizabeth (voice) / Mrs. Howard (voice)

Lara Jill Miller
Clifford (voice)

Masiela Lusha
Nina (voice)

Henry Winkler
Norville (voice)

Julie-Ann Dean
Daffodil (voice)

Candi Milo
Nina's Mom (voice) / Gray Puppy (voice) / Hester (voice)

Jess Harnell
Jorge (voice)

Ogie Banks
Zo (voice)

LaTonya Holmes
Flo (voice)

Susan Blu

Dionne Quan

Alan Oppenheimer

Kel Mitchell
Bill Mazer (voice)

Russi Taylor
Mrs. Zablione (voice)

Orlando Brown
Evan (voice)

Lauren Tom
Shun (voice)