David Kaufman
Danny Fenton / Danny Phantom (voice)

Grey DeLisle
Samantha 'Sam' Manson (voice)

Rickey D'Shon Collins
Tucker Foley (voice)

Colleen O'Shaughnessey
Jasmine 'Jazz' Fenton (voice)

Rob Paulsen
Jack Fenton (voice)

Kath Soucie
Madeline Fenton (voice)

Ron Perlman
Vice Principal Lancer (voice)

María Canals-Barrera
Paulina / Paulina (voice) / Paulina / Tracey (voice) / Paulina / Big Headed Kitt...

Martin Mull
Vlad Masters / Vlad Plasmius (voice)

Kevin Michael Richardson
Dragon (voice) / Skulker (voice) / Dragon / Paulina's Dad (voice)

Tara Strong
Penelope Spectra (voice) / Ember (voice) / Ember McLain (voice) / Tiffany Snow /...

James Sie
Kwan (voice) / Kwan / Camper (voice)

S. Scott Bullock
Dash Baxter (voice)

Laraine Newman
Mrs. Tetslaff (voice) / Pam (voice) / Mrs. Tetslaff / Witch Kid (voice) / Pam / ...

Dee Bradley Baker
Band Kid / Punk (voice)

James Arnold Taylor
Walker / Monster (voice) / Walker / Ghost Cop (voice)

June Angela
Principal Ishiyama (voice) / Harriet Chin (voice) /

Cree Summer
Valerie Gray (voice)

Jim Ward
Bertrand (voice) / Drive Through Voice Speaker Box / Ghost Walla (voice)

Mathew St. Patrick
Skulker (voice)