Your Friendly Neighborhood Spider-Man

Kari Wahlgren
May Parker (voice) / Roxanna Volkov (voice) / Mrs. Eberhardt (voice)

Zeno Robinson
Harry Osborn (voice) / Mr. Campbell (voice)

Hudson Thames
Peter Parker / Spider-Man (voice)

Colman Domingo
Norman Osborn (voice)

Eugene Byrd
Lonnie Lincoln (voice)

Grace Song
Nico Minoru (voice)

Cathy Ang
Pearl Pangan (voice)

Erica Luttrell
Asha (voice) / Emma (voice) / Mrs. Lincoln (voice) / Emma / Mrs. Lincoln (voice)

Roger Craig Smith
Coach Grayfield (voice) / Dmitri Smerdyakov (voice) / James 'Speed Demon' Sander...

Leilani Barrett
Big Donovan (voice) / Big Donavan (voice)

Zehra Fazal
Dr. Connors (voice) / Hot Rod (voice) / Dr. Connors (voice) / Susan O'Harra (vo...

Paul F. Tompkins
Bentley Wittman (voice)

Anairis Quinones
Carmilla Black (voice) / Maria Vasquez (voice)

Ettore Ewen
Bulldozer (voice)

Anjali Kunapaneni
Jeanne Foucault (voice) / Jeanne Foucault / Finesse (voice)

Aleks Le
Amadeus Cho (voice)

Phil LaMarr
Mr. Taylor (voice) / Mr. Lincoln (voice) / Mr. Taylor / Mr. Lincoln (voice)

Kellen Goff
Symbiotic Alien (voice) / Vincent Patilio (voice) / Vincent Patillo (voice)

Jonathan Medina
Mac Gargan (voice)

Alex Désert
Grift (voice)