Sadie Stanley
Kim Possible

Sean Giambrone
Ron Stoppable

Ciara Riley Wilson
Athena

Taylor Ortega
Shego

Connie Ray
Nana Possible

Issac Ryan Brown
Wade

Erika Tham
Bonnie Rockwaller

Maxwell Simkins
Young Drakken

Christy Carlson Romano
Poppy Blu

Nancy Cartwright
Rufus (voice)

Patton Oswalt
Professor Dementor

Todd Stashwick
Dr. Drakken

Alyson Hannigan
Dr. Ann Possible

Matt Clarke
James Timothy Possible

Owen Fielding
Tim

Connor Fielding
Jim

Michael P. Northey
Mr. Barkin

Patrick Sabongui
Dr. Glopman

Cedric Ducharme
Cool Todd

Kelcey Mawema
Student #1