Anthony Gonzalez
Miguel Rivera (voice)

Gael García Bernal
Héctor (voice)

Benjamin Bratt
Ernesto de la Cruz (voice)

Alanna Ubach
Mamá Imelda Rivera (voice)

Renee Victor
Elena Rivera (voice)

Ana Ofelia Murguía
Mamá Socorro "Coco" Rivera (voice)

Edward James Olmos
Chicharrón (voice)

Jaime Camil
Papá Enrique Rivera (voice)

Alfonso Arau
Papá Julio Rivera (voice)

Herbert Siguenza
Tío Oscar Rivera / Tío Felipe Rivera (voice)

Lombardo Boyar
Mariachi / Gustavo (voice)

Sofía Espinosa
Mamá Luisa Rivera (voice)

Dyana Ortelli
Tía Victoria Rivera (voice)

Gabriel Iglesias
Head Clerk (voice)

Selene Luna
Tía Rosita Rivera (voice)

Natalia Cordova-Buckley
Frida Kahlo (voice)

Carla Medina
Departure Agent (voice)

Blanca Araceli
Emcee (voice)

Polo Rojas
Abel Rivera (voice)

Montse Hernandez
Rosa Rivera (voice)