Danny Glover
Silas (segment "Long Black Song")

Wesley Snipes
George Du Vaul (segment "The Boy Who Painted Christ Black")

Lorraine Toussaint
Philomena (segment "The Reunion")

Tate Donovan
David (segment "Long Black Song")

Norman D. Golden II
Aaron (segment "The Boy Who Painted Christ Black")

Susanna Thompson
Beth Ann (segment "The Boy Who Painted Christ Black")

Jasmine Guy
Elna Du Vaul (segment "The Boy Who Painted Christ Black")

Tina Lifford
Sarah (segment "Long Black Song")

Carl Lumbly
Cal (segment "The Boy Who Painted Christ Black")

Bennet Guillory
Willie (segment "The Boy Who Painted Christ Black")

Danny Kamin
Mr. Harper (segment "Long Black Song")

Rae'Ven Larrymore Kelly
Lara (segment "The Boy Who Painted Christ Black")

Timothy Carhart
Prof. Daniel (segment "The Boy Who Painted Christ Black")

Summer Ross Jefferson
Young Philomena #1 (segment "The Boy Who Painted Christ Black")

Vanessa Bell Calloway
Miss Williams (segment "The Boy Who Painted Christ Black")

Winter Elaine Jefferson
Young Philomena #2 (segment "The Boy Who Painted Christ Black")

Amanda Addison
Young Beth Ann (segment "The Boy Who Painted Christ Black")

Kevin Jamal Woods
Clyde (segment "The Boy Who Painted Christ Black")

Ruth Beckford
Mrs. McClaren (segment "The Boy Who Painted Christ Black")

Yolanda King
Mrs. Crawford (segment "The Boy Who Painted Christ Black")