Edward G. Robinson
Caesar Enrico 'Rico' Bandello aka 'Little Caesar'

Douglas Fairbanks Jr.
Joe Massara

Glenda Farrell
Olga Stassoff

William Collier Jr.
Tony Passa

Sidney Blackmer
Big Boy

Ralph Ince
Pete Montana

Thomas E. Jackson
Sergeant Flaherty

Stanley Fields
Sam Vettori

Maurice Black
Little Arnie Lorch

George E. Stone
Otero

Armand Kaliz
De Voss

Nicholas Bela
Ritz Colonna

Ernie Adams
Cashier (uncredited)

Elmer Ballard
Undetermined Role (uncredited)

Ferike Boros
Mrs. Passa (uncredited)

Kernan Cripps
Detective (uncredited)

George Daly
Machine-Gunner (uncredited)

Adolph Faylauer
New Year's Celebrant (uncredited)

Ben Hendricks Jr.
Kid Bean (uncredited)

Al Hill
Rico's 'Butler' (uncredited)