Fred Allen
Sam "Slick" Brown (segment "The Ransom of Red Chief")

Anne Baxter
Joanna Goodwin (segment "The Last Leaf")

Jeanne Crain
Della (segment "The Gift of the Magi")

Farley Granger
Jim (segment "The Gift of the Magi")

Charles Laughton
Soapy (segment "The Cop and the Anthem")

Oscar Levant
William Smith (segment "The Ransom of Red Chief")

Marilyn Monroe
Streetwalker (segment "The Cop and the Anthem")

Jean Peters
Susan Goodwin (segment "The Last Leaf")

Gregory Ratoff
Behrman (segment "The Last Leaf")

Dale Robertson
Barney Woods (segment "The Clarion Call")

David Wayne
Horace (segment "The Cop and the Anthem")

Richard Widmark
Johnny Kernan (segment "The Clarion Call")

Joyce Mackenzie

Lee Aaker
J.B. Dorset (segment "The Ransom of Red Chief")

Richard Rober
Chief of Detectives (segment "The Clarion Call")

Fred Kelsey
Mr. Schultz (segment "The Gift of the Magi")

Richard Garrick
Doctor (segment "The Last Leaf")

Kathleen Freeman
Mrs. Dorset (segment "The Ransom of Red Chief") (uncredited)

Irving Bacon
Ebeneezer Dorset (segment "The Ransom of Red Chief") (uncredited)

William Vedder
Judge (segment "The Cop and the Anthem") (uncredited)